Publications

Peer-Reviewed Publications

Nath S.C., Day B., Harper L., Yee J., Hsu C.Y., Larijani L., Rohani L., Duan N., Kallos M., Rancourt, D.E.(2021). Fluid Shear Stress Promotes Embryonic Stem Cell Pluripotency via Interplay between β-catenin and Vinculin in Bioreactor Culture Cells. April 9. STEM CELLS

Cota P., Helmi S.A., Hsu C.Y., and Rancourt D.E. (2020). Cytokine Directed Chondroblast Trans-differentiation. JAK Inhibition Facilitates Direct Reprogramming of Fibroblasts to Chondroblasts. Cells. 9(1),191.

Borys B., Le A., Roberts E., Dang T., Rohanisarvestani L., Hsu C.Y., Wyma A., Rancourt, D.E., Gates I., Kallos M.S. (2019). Using Computational Fluid Dynamics (CFD) Modeling to understand Murine Embryonic Stem Cell Aggregate Size and Pluripotency Distributions in Stirred Suspension Bioreactors. Journal of Biotechnology. Oct 10; 304:16-27

Hsu C.Y., Walsh T., Borys, B.S., Kallos, M.S., and Rancourt D.E. (2018). An integrated approach towards the biomanufacturing of engineered cell therapy products in a suspension bioreactor. Molecular Therapy Methods and Clinical Development. Jun 15 (9) pp. 376–389. *COVER OF ISSUE* (pictured below)

Iqbal, S.M., Leonard, C., Regmi, S., De Rantere, D., Tailor. P., Ren, G., Ishida H., Hsu C.Y., Abubacker, S., Pang, D. SJ., Salo, P., Vogel, H.J., Hart, D.A., Waterhouse, C.C., Jay, G.D., Schmidt, T.A., and Krawetz, R.J. (2016). Lubricin / Proteoglycan 4 binds to and regulates the activity of Toll-Like Receptors In Vitro. Scientific Reports. Jan 11;6:

Wang, Y., Mostafa, N.Z., Hsu C.Y., Rose, L., Kucharski, C., Yan, J., Jiang, H., and Uludağ, H. (2013). Modification of human BMSC with nanoparticles of polymeric biomaterials and plasmid DNA for BMP-2 secretion. J. Surgical Res. Jul;183(1):8-17

Hsu C.Y., and Uludağ, H. (2012). Cellular Uptake Pathways of Lipid- Modified Cationic Polymers Employed For Gene Delivery to Primary Cells. Biomaterials. Nov;33(31):7834-48

Hsu C.Y., and Uludağ, H. (2012). A simple and rapid non-viral approach to effi ciently transfect primary tissue-derived cells using polyethylenimine. Nature Protocols. 7(5) 935-945.

Hsu C.Y., and Uludağ H. (2012). Nucleic-acid based gene therapeutics: delivery challenges and the modular design of non-viral gene carriers and expression cassettes to overcome intracellular barriers for sustained targeted expression. J. Drug Targ. Feb 6.

Hsu C.Y., Hendzel, M., and Uludag, H. (2011). Improved Transfection Effi ciency of an Aliphatic lipid Substituted 2 kDa Polyethylenimine is Attributed to Enhanced Nuclear Association and Uptake in Rat Bone Marrow Stromal Cell. J. Gene Med. Jan;13(1):46-59.

Neamnark A., Suwantong O., Bahadur R.K., Hsu C.Y., Supaphol P., Uludağ H. (2009). Aliphatic lipid substitution on 2 kDa polyethylenimine improves plasmid delivery and transgene expression. Mol Pharm. 2009 Nov-Dec;6 (6):1798-815.

Clement, B.A., Hsu C.Y., Kucharski, C., Lin, X., Rose, L., and Uludağ, H. (2009) Non-viral delivery of basic fibroblast growth factor gene to bone marrow stromal cells. Clin Orthop Relat Res. Dec;467(12):3129-37.

Hsu C.Y., and Uludağ, H. (2008). Effect of size and topology of DNA molecules on intracellular delivery with non-viral gene carriers. BMC Biotech. 8: 23.